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Lubiprostone Oral Capsule

What is this medicine?

LUBIPROSTONE (loo bi PROS tone) is a laxative. It is used to treat chronic constipation and constipation caused by opioids (certain prescription pain medicines). It is also used to treat adult women with irritable bowel syndrome who have constipation.

How should I use this medicine?

Take this medicine by mouth with water. Take it as directed on the prescription label at the same time every day. Do not cut, crush or chew this medicine. Swallow the capsules whole. Take it with food. Keep taking it unless your health care provider tells you to stop.

Talk to your health care provider about the use of this medicine in children. It is not approved for use in children.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions (skin rash, itching or hives; swelling of the face, lips, or tongue)

  • feeling faint or lightheaded, falls

  • new or worsening stomach pain

  • severe or prolonged diarrhea

  • vomiting

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • headache

  • loose stools

  • nausea

What may interact with this medicine?

  • medicines that treat diarrhea

  • methadone

  • other medicines for constipation

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Where should I keep my medicine?

Keep out of the reach of children and pets.

Store at 25 degrees C (77 degrees F). Protect from light. Avoid exposure to extreme heat/cold. Throw away any unused medicine after the expiration date.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • history of blockage in your bowels

  • history of stool (fecal) impaction

  • liver disease

  • stomach cancer

  • an unusual or allergic reaction to lubiprostone, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Visit your health care provider for regular checks on your progress. Tell your health care provider if your symptoms do not start to get better or if they get worse.

NOTE:This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider. Copyright© 2021 Elsevier